For Healthcare Professionals
Detailed summaries of key clinical papers on organ transplantation, machine preservation and factors affecting post-transplant outcomes, plus video presentations by leading experts in the field on their clinical experience with machine preservation.
A summary of key evidence in organ preservation and transplantation is offered below:
- Use of machine perfusion in all types of donor kidneys
- Data on the impact and mechanisms of delayed graft function
- The basic science behind the mechanism of action during machine perfusion
- Cost-effectiveness studies based on LifePort Kidney Transporter
- Evaluation of renal resistance parameters for discard/transplantation
- Details of the impact of early allograft dysfunction
- Pilot clinical studies of hypothermic machine preservation in liver transplantation
- The potential for a donor risk index
- Economic impact of liver transplantation, especially in high risk donor organs
- Increased primary non-function in deceased donor kidneys flushed with HTK solution
- Evaluation of the important components of UW Solution
- Association of HTK solution and reduced graft survival in deceased donor livers
- Review of HTK vs. UW preservation solution in pancreata transplantation
Key experts in the field of transplantation present their clinical experience with machine perfusion. These videos have been prepared to answer frequently asked questions, including:
- Can machine preservation close the gap between demand and availability of donor organs by utilizing marginal kidneys?
- What are the logistical and practical issues in starting a machine preservation program?
- Is it possible to have a national machine preservation program?
- Can machine preservation extend cold time to enable transplantation at optimal times, without harming the organ?
- What clinical experience exists in machine preservation of livers prior to transplantation?
Click here to see leading transplant surgeons share their clinical experience:
- Dr. A. Osama Gaber – Director of Transplantation and Vice Chairman of Surgery, The Methodist Hospital System, Houston, Texas, USA
- The benefits of machine perfusion in DBD kidneys
- Dr. Andrew Ready – Consultant Renal and General Surgeon Department of Renal Surgery at the New Queen Elizabeth Hospital Birmingham, UK
- Addressing recipient factors: optimising the outcomes post-transplant
- Professor Benoit Barrou – Groupe Hospitalier Pitié Salpêtrière, Paris, Head of the Kidney Transplantation Program, Department of Urology and Transplant Surgery, France
- Why should kidneys be machine perfused?
- Dr. James V. Guarrera – Associate Professor of Surgery, Surgical Director of Adult Liver Transplantation, Columbia University Medical Center/ New York Presbyterian Hospital, USA
- Reducing early allograft dysfunction and improving outcomes in liver transplantation with hypothermic machine preservation