SPS-1®: UW Solution for the flushing and static cold storage of kidneys

Delivering the gold standard in organ preservation solutions.

Organ Recovery Systems offers SPS-1, the trusted static preservation solution having the same composition as originally formulated by F.O. Belzer, MD* and James Southard, PhD*, at the University of Wisconsin®*

 

* Belzer UW® and University of Wisconsin® are registered trademarks of the Wisconsin Alumni Research Foundation and the Board of Regents of the University of Wisconsin System, respectively. Organ Recovery Systems, Inc. has no affiliation with the Wisconsin Alumni Research Foundation, the Board of Regents of the University of Wisconsin System, F.O. Belzer and/or James Southard, PhD.
Product Details
  • Available in 1 or 2 Liter bags

  • Two-year shelf life

  • Ambient storage, cool before use

  • User-friendly bag with graduated marks

  • No filter required

  • Intended for the flushing and cold storage of kidney, liver and pancreas organs at the time of removal from the donor in preparation for storage, transportation and eventual transplantation into a recipient

  • Manufactured to FDA cGMP and ISO 13485 and ISO 9001 standards in the USA
Constituents
Amount/1000 mL

Hydroxyethyl Starch (HES)

50.0 g

Lactobionic Acid (as Lactone)

35.83 g

Potassium Phosphate monobasic

3.4 g

Magnesium Sulfate heptahydrate

1.23 g

Raffinose Pentahydrate

17.83 g

Adenosine

1.34 g

Allopurinol

0.136 g

Glutathione (reduced form)

0.922 g

Potassium Hydroxide

5.61 g

Sodium Hydroxide/Hydrochloric Acid

Adjust to pH 7.4

Sterile Water for Injection (SWI)

To 1000 mL Volume

Precaution

The donor organ must be flushed free of the SPS-1 (UW Solution) prior to the reperfusion. The organ must be flushed with physiological solution to prevent occurrence (in the recipient) of potentially serious cardiovascular complications such as hyperkalemic cardiac arrest or bradyarrhythmia. This is necessary because of the high concentration of potassium in the solution. These precautions must be taken prior to re-implantation (or transplantation) to avoid cardiac arrest in the recipient.

SPS-1 (UW Solution) includes components (allopurinol and pentafraction) which individually have caused hypersensitivity reaction in patients.

SPS-1 (UW Solution) IFU