Kidney

Browse 4 Items
Using renal resistance to predict outcomes
15 May 2014  //  Clinical Evidence

Using renal resistance to predict outcomes

Renal resistances during machine perfusion are believed to be predictive of transplant outcomes and are frequently used as a reason to discard kidneys prior to transplant.1 However, renal resistance threshold values have never been studied in a prospective randomized study. In this trial, 2,336 kidney pairs (672 recipients) were studied to examine the prognostic value of renal resistance on delayed graft function (DGF), primary non‐function (PNF) and graft survival of deceased donor kidneys. Read More ›
Machine perfusion of donation after cardiac death (DCD) kidneys
21 February 2014  //  Clinical Evidence

Machine perfusion of donation after cardiac death (DCD) kidneys

The Machine Preservation Trial was the first prospective, international randomized controlled trial comparing machine perfusion on LifePort with static cold storage.1 Rates of 1-year graft survival are significantly reduced in patients who experience delayed graft function (DGF).2 The use of donation after cardiac death (DCD) kidneys and expanded criteria donor (ECD) kidneys is increasing as the number of standard criteria donor (SCD) organs and organs donated after brain death decreases.3 Read More ›
Machine perfusion of expanded criteria donor (ECD) kidneys
10 January 2014  //  Clinical Evidence

Machine perfusion of expanded criteria donor (ECD) kidneys

The effects of machine perfusion (MP) versus static cold storage (SCS) on delayed graft function (DGF) and early graft survival in expanded criteria donor (ECD) kidneys was examined in a prospective, randomized international clinical study. Read More ›
Predicting 1-year outcomes using machine measured renal resistance
10 February 2013  //  Clinical Evidence

Predicting 1-year outcomes using machine measured renal resistance

A retrospective analysis was undertaken to investigate the correlation of different donor parameters such as sex, age, race, glomerular filtration rate, terminal creatinine level, and various renal allograft biopsy parameters and machine-measured renal resistance (MMRR) with 1-year renal function and allograft outcomes. Read More ›