The Clinical Need in Renal Transplantation

Long-term survival of kidney grafts is not improving despite better donor management and improved immunosuppression.1

The number of people needing dialysis for end-stage renal failure is likely to double in the next 10 years.2

Finding ways to help bridge the gap between demand and supply of organs is vital.

Long-term survival of kidney graft according to donor type
1-and-3-year graft survival for all deceased donor kidneys is better with LifePort Kidney Transporter compared with static cold storage

Transforming Outcomes with LifePort Kidney Transporter

Combining innovative technology, user-friendly design and an advanced technology platform, LifePort Kidney Transporter has revolutionized kidney preservation. Compelling evidence shows that LifePort can improve the odds of a good outcome.

Both 1-year and 3-year graft survival for all Deceased Donor Kidneys (DCD) is better with LifePort Kidney Transporter when compared with cold static storage.3,4

Clinical Challenges in Kidney Transplantation

Graft survival in kidney transplantation is strongly impacted by the occurrence of DGF, particularly in kidneys from marginal donors.

Delayed Graft Function (DGF): the clinical challenge

Graft survival in kidney transplantation is strongly impacted by the occurrence of DGF, particularly in kidneys from marginal donors.5,6

Impact of Delayed Graft Function

  • Negative impact on long-term graft survival6-8
  • Increased risk of acute rejection6
  • Increased healthcare costs6
  • Poor outcomes for the patient6

Transforming outcomes, transforming lives

LifePort Kidney Transporter helps surgeons transplant kidneys with confidence, even kidneys considered to be from marginal donors. State-of-the-art preservation with LifePort has proven to significantly reduce the risk of DGF for all kidney donor types compared with cold static storage.5,6

Routinely protecting and preserving expanded criteria donor (ECD) kidneys and DCD kidneys with LifePort Kidney Transporter could make all the difference.6

LifePort display panel captures detailed performance data in real time

Transforming knowledge: improving decision making

The fully portable LifePort Kidney Transporter captures and displays key performance data in real time.

Onboard digital readouts show patient ID number, blood type, temperature, diastolic and systolic pressure, flow, resistance and perfusion time.

The on-board GPS/GPRS system offers capability for routine transmission of location and key performance data. Perfusion related data is available for rapid download via USB port.

LifePort Kidney Perfusion Circuit

Custom-made for Kidney Perfusion

The self-contained Perfusion Circuit cradles the organ in cold physiologic solution. A custom-made disposable cannula, comfortably supported by an adjustable mount, allows swift connection of the kidney to LifePort Kidney Transporter, even for organs with the most challenging anatomies. And the entire disposable apparatus set – complete with organ cassette, pressure sensor and preservation solution – loads and unloads in one easy motion.

LifePort machine perfusion reduces the impact of Delayed Graft Function

Clinical Evidence Supports the Use of LifePort Kidney Transporter

The Machine Preservation Trial, an international prospective randomized controlled clinical trial to investigate the incidence and risk of delayed graft function (DGF) in kidneys preserved by machine perfusion prior to transplantation, demonstrated that machine perfusion with LifePort Kidney Transporter significantly reduces all types of deceased donor kidneys.3–6

Full Summary of the Clinical Evidence for LifePort Kidney Transporter ›

References
1. OPTN & SRTR Annual Data Report 2011, Kidney. Available at:
http://srtr.transplant.hrsa.gov/annual_reports/2011/pdf/2011_SRTR_ADR.pdf (PDF Accessed 29/11/2013).
2. Collins AJ, et al. Clin J Am Soc Nephrol 2009;4(Supplement 1):S5-S11.
3. Moers C., et al. N Engl J Med 2009;360(1):7–19.
4. Moers C., et al. N Engl J Med 2012;366(8):770–1.
5. Treckmann J., et al. Transplant Int 2011;24(6):548–54.
6. Jochmans I., et al. Ann Surg 2010;252(5):756–64.

 

LifePort Kidney Transporter IFU

Our local surgeons are really pleased with the new Universal SealRing cannula; they like the way in which it hugs the artery/patch and does not cause any harm to the intima of the artery. We have also found that they are easy to use and don’t leak at all.