KPS-1®: UW Solution for machine perfusion of kidneys

Delivering the gold standard in organ preservation solutions

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* University of Wisconsin® is a registered trademark of the Board of Regents of the University of Wisconsin System. Organ Recovery Systems, Inc. has no affiliation with the Board of Regents of the University of Wisconsin System, F.O. Belzer, MD and/or James Southard, PhD.

Product Details

  • Available in 1 Liter bags
  • Two-year shelf life
  • Ambient storage, cool before use
  • Intended to be used for flushing and continuous hypothermic machine perfusion of kidneys at the time of their removal from the donor in preparation for storage, transportation and eventual transplantation into a recipient
  • Manufactured to FDA cGMP and ISO 13485 and ISO 9001 standards in the USA

Constituents

Calcium chloride (dehydrate)
Sodium hydroxide
HEPES (free acid)
Potassium phosphate (monobasic)
Mannitol (USP)
Glucose, beta D (+)
Sodium gluconate
Magnesium gluconate D (–) gluconic acid, hemimagnesium salt
Ribose, D (–)
Hydroxyethyl starch (HES)
Glutathione (reduced form)
Adenine (free base)
Sterile water for injection (SWI)

Amount/1000 mL

0.068 g
0.70 g
2.38 g
3.4 g
5.4 g
1.80 g
17.45 g
1.13 g
0.75 g
50.0 g
0.92 g
0.68 g
To 1000 mL volume

Concentration, mM

0.5
10
25
30
10
80
5
5
n/a
3
5
n/a

Precaution

KPS-1, Kidney Perfusion Solution includes constituents (Hydroxyethyl starch [HES]), which have caused hypersensitivity reactions in some patients. Physicians should be alert to treat possible reactions.

KPS-1 IFU