A retrospective analysis of SRTR data (2005 – 2024) by Valencia et al out of Mayo Clinic published in Transplant International shows delayed graft function (DGF) to be a strong predictor of adverse long-term outcomes, up to a decade. Researchers conclude DGF warrants targeted prevention strategies and intensified follow-up.

The graphical abstract tells the story:

Targeted Prevention of DGF with LifePort Kidney Transporter 

              In Moers et al 2009, hypothermic machine perfusion (HMP) with LifePort Kidney Transporter (LKT) was associated with a statistically significant decrease in DGF compared to static cold storage. 10-year follow up data shows the 1-year, 3-year and 10-year graft survival rates were better in those kidneys that received HMP with LKT.  We agree with the authors of this article—targeted prevention strategies to reduce incidence of DGF in kidney transplant recipients should be utilized.  HMP with LKT has the clinical evidence to back it up as a DGF prevention strategy. Less DGF in the short term means better graft survival in the long term.

Read the full study here: https://pmc.ncbi.nlm.nih.gov/articles/PMC13314580/