Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation

February 19, 2020

In 2009, Moers et al. published the largest ever randomized controlled trial comparing paired kidneys that were either subjected to hypothermic machine perfusion (HMP) or cold storage (CS). This study included 336 kidney pairs that were randomized to either the HMP group or CS group.

Overall, they found that:

  • HMP significantly reduced the risk of delayed graft function (DGF)
  • Duration of DGF was shorter in the HMP group
  • One-year graft survival was significantly higher in the HMP group

They concluded that hypothermic machine perfusion reduces the incidence of DGF as well as reducing the risk of graft failure in the first year, resulting in improved 1-year graft survival compared to kidneys preserved by static cold storage.

Read the full article here: https://www.nejm.org/doi/full/10.1056/NEJMoa0802289

The Latest

Check out the most recent posts

Canadian Transplant Summit

Canadian Transplant SummitMarch 23, 2020September 22, 2020 to September 26, 2020 Fairmont Winnipeg, Manitoba, Canada2 Lombard Place, Winnipeg, MB R3B 0Y3 The vision of the Canadian Transplant Summit is to connect members of the Canadian Society of Transplantation with...

NATCO Annual Meeting

NATCO Annual MeetingMarch 17, 2020August 4, 2020 to August 7, 2020 Sheraton Kansas City Hotel at Crown Center 2345 McGee StKansas City, MO 64108 The focus for the NATCO Annual Meeting is working together towards improved donation and transplant outcomes through shared...