Renal Resistance Thresholds During HMP and Transplantation Outcomes

Clinical Evidence

Renal Resistance Thresholds During HMP and Transplantation Outcomes

Renal Resistance Thresholds During HMP and Transplantation Outcomes

Sandal et al. sought to study renal resistance (RR) as an independent predictor of long-term graft survival in kidney transplant recipients whose allografts underwent HMP. They included in their analysis 422 deceased donor kidney transplants of which 59% were from ECD donors and 8% were from DCD donors.

They found that:

  • An increased risk of death censored graft failure was observed when the terminal RR threshold of ≥ 0.4 mmHg/mL/min was used, and that risk was decreased when a terminal RR threshold of ≥ 0.2 mmHg/mL/min was used 
  • There was no significant risk of DGF with increased terminal RR threshold

Overall, they concluded that terminal RR and repeated measurements of RR in kidney grafts undergoing HMP are associated with long term graft survival.

Read the full article here: https://doi.org/10.1111/tri.13146

Tagged In:

DGF, Graft Survival, HMP, Kidney, Renal Resistance

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