Use of Machine Perfusion to Increase the Number of Expanded Criteria Deceased Donor Kidney Transplants: A Pharmacoeconomic Analysis

Clinical Evidence

Use of Machine Perfusion to Increase the Number of Expanded Criteria Deceased Donor Kidney Transplants: A Pharmacoeconomic Analysis

Use of Machine Perfusion to Increase the Number of Expanded Criteria Deceased Donor Kidney Transplants: A Pharmacoeconomic Analysis

A recent pharmacoeconomic study from Brazil by Tedesco Silva Junior et al. sought to evaluate the cost-effectiveness and budgetary impact of incorporating hypothermic machine perfusion (HMP) for preserving extended criteria donor (ECD) kidneys.   

They found that using HMP for ECD kidneys and static cold storage (SCS) for standard criteria donors:  

  • Increased transplants by 1123 
  • Decreased patients on dialysis by 815 
  • Decreased patient deaths by 120 
  • Incurred an additional cost of 4,453,749 USD, but on budget impact analysis realized resource savings by year 5

Overall, they concluded that using HMP for ECD kidneys is a cost-effective strategy. They found that they could increase the number of transplants, reduce the number of patients on dialysis, and decrease the mortality rate with a reasonable cost-effectiveness ratio. 

Read the full article here: https://journals.lww.com/transplantationdirect/fulltext/2024/08000/use_of_machine_perfusion_to_increase_the_number_of.3.aspx

Tagged In:

ECD, Financial, HMP, Kidney

The Latest

Check out the most recent posts

ASTS Winter Symposium

ASTS Winter Symposium

January 16 - January 19, 2025 Sheraton Grand Hotel5594 W Wild Horse Pass BlvdPhoenix, AZ 85226 The American Society of Transplant Surgeons is dedicated to saving and improving the lives of others through the power of organ donation and transplant surgery. This event...

NATCO Annual Meeting

NATCO Annual Meeting

February 23 - February 26, 2025 Hyatt Regency Hill Country Resort & Spa 9800 Hyatt Resort DrSan Antonio, TX 78251 NATCO is dedicated to advancing education, promoting certifications, and furthering the professional development of donation and transplant...

UNOS Transplant Management Forum

UNOS Transplant Management Forum

May 5 - May 7, 2025 San Antonio Marriott Rivercenter on the River Walk 101 Bowie St San Antonio, TX UNOS is the private, non-profit organization that manages the nation's organ transplant system under contract with the federal government. Transplant administrators...