In the era of KDPI, Montenovo et al. sought to assess the impact of the use of machine perfusion (MP) on the incidence of delayed graft function (DGF) in the different groups of kidney grafts classified by kidney donor profile index (KDPI). They used the UNOS database from January 2008 to Sept 2017 with over 100,000 recipients meeting inclusion criteria.
They found that:
- Univariate analysis – MP significantly decreased development of DGF across all groups
- Multivariate analysis – MP significantly decreased DGF in higher KDPI score groups (KDPI > 60)
Overall, they concluded that the results should encourage the use of MP versus static cold storage especially from donors with a higher risk kidney donor profile index (KDPI>60).
Read the full article here: https://www.ncbi.nlm.nih.gov/pubmed/32133939
Check out the most recent posts
LifePort Liver Transporter by Organ Recovery Systems Wins Fast Company’s 2023 Innovation by Design Award in the ‘Health’ Category
Organ Recovery Systems (ORS) is honored to announce that its LifePort Liver Transporter was selected as the winner in the ‘Health’ category in Fast Company’s Innovation by Design Awards for 2023. The Innovation by Design Awards, which can be found in the September...
October 18, 2023 to October 21, 2023 Mandalay Bay3950 Las Vegas BlvdLas Vegas, NV 89119 The International Society for Donation and Transplantation is the organization advancing donation through science, developing professionals and inspiring networks supporting organ...
The first use of hypothermic machine perfusion in Korea to recover a procured kidney graft and prevent prolonged cold ischemic time: a case report
Shin et al. reported on the first deceased donor kidney transplant case using hypothermic machine perfusion (HMP) on Jeju Island, Korea. A single deceased donor with several hours of marginal oxygen saturation had both kidneys assigned to Jeju Island. Due to...
Novel Oxygenation Technique for Hypothermic Machine Perfusion of Liver Grafts: Validation in Porcine Donation after Cardiac Death (DCD) Liver Model
In a pre-clinical study using a porcine DCD model, Panayotova et al. sought to validate the novel technique of oxygen “pre-charge” for hypothermic machine perfusion (HMP) using the LifePort Liver Transporter. The study evaluated the effects of this preservation method...