Machine Perfusion Decreases Delayed Graft Function in Donor Grafts With High Kidney Donor Profile Index

Clinical Evidence

Machine Perfusion Decreases Delayed Graft Function in Donor Grafts With High Kidney Donor Profile Index

Machine Perfusion Decreases Delayed Graft Function in Donor Grafts With High Kidney Donor Profile Index

In the era of KDPI, Montenovo et al. sought to assess the impact of the use of machine perfusion (MP) on the incidence of delayed graft function (DGF) in the different groups of kidney grafts classified by kidney donor profile index (KDPI). They used the UNOS database from January 2008 to Sept 2017 with over 100,000 recipients meeting inclusion criteria.

They found that:

  • Univariate analysis – MP significantly decreased development of DGF across all groups
  • Multivariate analysis – MP significantly decreased DGF in higher KDPI score groups (KDPI > 60)

Overall, they concluded that the results should encourage the use of MP versus static cold storage especially from donors with a higher risk kidney donor profile index (KDPI>60).

Read the full article here: https://www.ncbi.nlm.nih.gov/pubmed/32133939

Tagged In:

DGF, HMP, KDPI, Kidney

The Latest

Check out the most recent posts

ASTS Winter Symposium

ASTS Winter Symposium

January 16 - January 19, 2025 Sheraton Grand Hotel5594 W Wild Horse Pass BlvdPhoenix, AZ 85226 The American Society of Transplant Surgeons is dedicated to saving and improving the lives of others through the power of organ donation and transplant surgery. This event...

NATCO Annual Meeting

NATCO Annual Meeting

February 23 - February 26, 2025 Hyatt Regency Hill Country Resort & Spa 9800 Hyatt Resort DrSan Antonio, TX 78251 NATCO is dedicated to advancing education, promoting certifications, and furthering the professional development of donation and transplant...